Lars S Maier Selected Research

Phosphotransferases (Kinase)

4/2024	Ca2+/calmodulin-dependent kinase IIδC-induced chronic heart failure does not depend on sarcoplasmic reticulum Ca2+ leak.
10/2020	The oral Ca/calmodulin-dependent kinase II inhibitor RA608 improves contractile function and prevents arrhythmias in heart failure.
12/2018	Activation of protein phosphatase 1 by a selective phosphatase disrupting peptide reduces sarcoplasmic reticulum Ca2+ leak in human heart failure.
5/2013	The Ca-calmodulin dependent kinase II: a promising target for future antiarrhythmic therapies?
3/2007	Remodeling of excitation-contraction coupling in the heart: inhibition of sarcoplasmic reticulum Ca(2+) leak as a novel therapeutic approach.

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Lars S Maier Research Topics

Disease

80	Heart Failure 04/2024 - 01/2002
19	Atrial Fibrillation 11/2023 - 04/2010
15	Cardiomegaly (Heart Hypertrophy) 01/2020 - 05/2003
12	Cardiac Arrhythmias (Arrythmia) 09/2023 - 11/2009
11	ST Elevation Myocardial Infarction 01/2023 - 08/2012
10	Cardiomyopathies (Cardiomyopathy) 12/2021 - 02/2010
10	Myocardial Infarction 10/2021 - 12/2012
10	Heart Diseases (Heart Disease) 01/2020 - 01/2009
8	COVID-19 02/2024 - 01/2020
8	Hypertrophy 01/2021 - 05/2003
5	Fibrosis (Cirrhosis) 03/2024 - 10/2012
5	Hemorrhage 11/2023 - 12/2017
5	Sleep Apnea Syndromes (Sleep Apnea) 02/2022 - 01/2018
5	Cardiogenic Shock 01/2021 - 12/2017
5	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 05/2020 - 03/2010
5	Tachycardia (Tachyarrhythmias) 01/2019 - 08/2014
5	Myocardial Ischemia (Ischemic Heart Diseases) 06/2018 - 10/2009
5	Contracture 05/2010 - 01/2002
4	Shock 05/2024 - 01/2018
4	Acute Kidney Injury (Acute Renal Failure) 02/2024 - 01/2017
4	Coronary Artery Disease (Coronary Atherosclerosis) 09/2023 - 12/2017
4	Mitral Valve Insufficiency (Mitral Regurgitation) 05/2023 - 01/2020
4	Chronic Renal Insufficiency 01/2023 - 06/2016
4	Hypertension (High Blood Pressure) 01/2023 - 03/2007
4	Infarction (Infarctions) 07/2021 - 11/2018
4	Unstable Angina 01/2021 - 08/2015
4	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 03/2013
4	Chest Pain (Chest Pains) 01/2021 - 01/2014
3	Stroke (Strokes) 11/2023 - 12/2017
3	Central Sleep Apnea (Central Sleep Apnea Syndrome) 06/2021 - 05/2018
3	Infections 02/2021 - 02/2006
3	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 09/2020 - 05/2003
3	Non-ST Elevated Myocardial Infarction 02/2020 - 03/2018
3	Systolic Heart Failure 01/2017 - 03/2011
3	Neoplasms (Cancer) 11/2013 - 06/2007
3	Acidosis 06/2013 - 12/2007
2	Angina Pectoris 09/2023 - 06/2018
2	Acute Coronary Syndrome 01/2023 - 11/2019
2	Ventricular Tachycardia 01/2023 - 02/2010
2	Disease Progression 01/2023 - 04/2012
2	Left Ventricular Dysfunction 11/2022 - 09/2020
2	Diabetes Mellitus 10/2021 - 01/2020
2	Thrombocytopenia (Thrombopenia) 01/2021 - 03/2007
2	Albuminuria 01/2021 - 01/2017
2	Thrombosis (Thrombus) 01/2021 - 03/2007
2	Stable Angina 02/2020 - 10/2009
2	Apnea 01/2020 - 05/2018
2	Hypoxia (Hypoxemia) 01/2020 - 03/2010

Drug/Important Bio-Agent (IBA)

42	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 04/2024 - 05/2003
17	Calcium-Calmodulin-Dependent Protein KinasesIBA 08/2017 - 12/2006
16	Proteins (Proteins, Gene)FDA Link 01/2020 - 05/2003
14	Ranolazine FDA Link 01/2023 - 10/2009
9	Biomarkers (Surrogate Marker)IBA 05/2024 - 06/2016
8	Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA 04/2024 - 05/2003
7	Protein Isoforms (Isoforms)IBA 01/2020 - 05/2003
6	Coe Comfort (FITT)IBA 01/2023 - 08/2012
6	SodiumIBA 01/2021 - 03/2012
5	Calmodulin (Calcium-Dependent Activator Protein)IBA 04/2024 - 03/2007
5	Phosphotransferases (Kinase)IBA 04/2024 - 03/2007
5	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2023 - 06/2006
5	pro-brain natriuretic peptide (1-76)IBA 01/2023 - 01/2016
5	Messenger RNA (mRNA)IBA 01/2021 - 04/2008
5	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2017 - 11/2003
5	Adrenergic Agents (Adrenergic Drugs)IBA 10/2014 - 02/2010
4	Interleukin-6 (Interleukin 6)IBA 04/2024 - 05/2021
4	Ion Channels (Ion Channel)IBA 09/2023 - 06/2009
4	CalciumIBA 01/2020 - 07/2006
4	CatecholaminesIBA 12/2017 - 02/2010
3	CreatinineIBA 02/2024 - 01/2020
3	Ethanol (Ethyl Alcohol)IBA 01/2023 - 06/2010
3	empagliflozinIBA 01/2021 - 01/2018
3	RNA (Ribonucleic Acid)IBA 01/2021 - 01/2020
3	Hexosaminidases (Hexosaminidase)IBA 01/2021 - 06/2016
3	Protein Phosphatase 1IBA 12/2018 - 01/2017
3	Adrenergic Receptors (Adrenergic Receptor)IBA 05/2017 - 04/2015
3	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 08/2013 - 03/2007
3	Oxygen (Dioxygen)IBA 09/2012 - 03/2010
2	GadoliniumIBA 03/2024 - 11/2021
2	AdrenomedullinIBA 02/2024 - 01/2020
2	Dipeptidyl-Peptidases and Tripeptidyl-PeptidasesIBA 02/2024 - 09/2023
2	C-Reactive ProteinIBA 02/2024 - 05/2021
2	Hemoglobins (Hemoglobin)IBA 11/2023 - 01/2021
2	TicagrelorIBA 01/2023 - 11/2019
2	Oxidants (Oxidizing Agents)IBA 02/2022 - 03/2013
2	Troponin T (Troponin T1)IBA 11/2021 - 12/2017
2	Glucose (Dextrose)FDA LinkGeneric 05/2021 - 01/2021
2	Heparin (Liquaemin)FDA LinkGeneric 01/2021 - 03/2007
2	TroponinIBA 01/2021 - 01/2014
2	Neprilysin (Neutral Endopeptidase)IBA 05/2020 - 01/2017
2	DysferlinIBA 01/2020 - 01/2017

Therapy/Procedure

32	Therapeutics 05/2023 - 06/2007
17	Percutaneous Coronary Intervention 09/2023 - 12/2012
5	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 10/2021 - 12/2012
3	Extracorporeal Membrane Oxygenation 01/2023 - 01/2021
3	Heart-Assist Devices 09/2020 - 08/2018
3	Renal Replacement Therapy (Therapies, Renal Replacement) 01/2020 - 12/2017
2	Resuscitation 05/2024 - 11/2009
2	Catheter Ablation 11/2022 - 01/2018
2	Patient Readmission 10/2021 - 11/2018
2	Length of Stay 02/2021 - 12/2018